Some of us are forced to live in the real world, I have patched so many holes in that location I cannot count and 90% of them never give any more trouble to the end of the tire. One just must not be an idiot in how you approach it.
My back entry drive is dirt and made up of construction waste from a half century ago plus, when it rains the runoff can expose as many as 100 old nails just in my back frontage alone. I was forced years ago to learn optimum tire patching and now down to a science, I no longer even remove the tires in most cases any longer. Tire road hazard warranties there mean countless hours waiting for the free tire fixes and I'm usually done with one in 3 minutes.
Give it some thought like with all other things, the people who tell you it is 'unsafe' are the ones selling you the tires, or closely connected to them. Or barring that uneducated as to what works fine in real life.
I often turn in old tires with up to 4 plugs in them and it freaks the tire guys out. The tires went on to get max life in most cases or suncracked to be declared dead early here in the Texas heat.
The unmentioned max issue there will be what has the OTHER END of the screw done as far as flexing around sideways when rolling over rocks, etc. to damage the true sidewall further up/out, and why leaving the screw in place is sheer stupidity, you remove them as soon as you see them unless you want a fatal catastrophic blowout. You at the least want to know how long that screw is.