Are you talking about running it to the four speakers in the doors? If you have the stock speakers, it is not near worth putting an amp to them. If you are/have upgraded your speakers, please tell what they are so we can look up the specks and see if that amp would be a good addition.
It just depends. What size type and line of pioneers. Before I get jumped on by size and type I mean there are different options. You can get a 5x7/6x8 or with a bracket a 5 1/4" either standard or component can fit, or a 6 1/2" component can fit with some adjusting and modification. With speakers it is pretty much true that the more you spend the better sound quality you get. Pioneers walmart line is not the best, they sound better than stock but not the best. I can't say anything about their higher end line.
However, I have Kenwood KFC's in my F-150 that I really like. They are running only from a Kenwood Excelon Head unit.
I have Infinity Kappa's in my Foci that I like but they are also just of a Kenwood Excelon.
If the amp puts out that many watts, you are going to want to find out the RMS per channel as well as the peak per channel at 4 ohms and find some speakers that can take what the amp says it can put out. If you have a link to the specks on the amp, I am sure more help and recommendations can be given.