The only issue would be getting too BIG of a wastegate.. which in turn causes difficulties for the boost controller... it makes it harder to control
I run the 38mm TIAL and I have had no issues at all and I run more boost than most of the people on the board.
[B]1951 McCormick FARMALL M
2007 MINI Cooper S Turbo... new project car
1998 Chevy 3500 Ext cab, long bed, 4x4, duelly, turbo diesel
2004 Harley V-Rod.... sex on wheels
2011 Harley Electra Glide Ultra Limited