Reliability IMHO is mainly in the tune, if you want to do forced induction right you will install it and then have it tuned on the dyno with air fuel readings. Once you tune it for optimal power then you should back off the settings (boost, timing, fuel perhaps) some for saftey if your going to drive it day to day. Especially if you live in a part of the country where the weather changes dramatically between the seasons, a perfect and safe tune on a 100 degree day might not be safe for when its 40 degree's outside and the air is more dense. If you can get a chip with multiple tunes that is the best option, that way you can tune it for race gas, regular gas, or whatever and have that ready at the flip of a switch.
Also all types of forced induction are somewhat harder on the engine, but when properly tuned it should be minimal overall, unless of course your going to run it WOT every time you get in it. If your going to do that, then you should build it like your planning on rallying with it :)
2004 Sonic Blue SVTF
"It is better to make torque at high rpm than at low rpm, because you can take advantage of *gearing*."