Bent rims will be your most likely issue. 5-spokes are relatively soft wheels and are easy to bend. That said, I ran my 5-spokes with two bent wheels for about a year before upgrading. The only problem I had was a slight vibration through the steering wheel (kind of like a wheel out of balance but not as bad) and a thumping noise that could easily be drowned out by the radio.
Hatch Nation #13 : Rally Revolution #13 : ROTM Jan '13
It's Bryan, not Brian
RSVT-170 Build in Progress
Rusty is dead