From the instructions:
• XSVI-5524-NAV - Ford interface 2011-up
• FRST-2 - Ford RSE/SYNC/THX Retention Interface 2012-up
• 40-EU10 Multi-App antenna adapter
Note that SYNC is expensive and fairly limited here - i.e. you only have control of USB with it, not the radio itself, you need rear RCA AUX inputs on the new radio, and you need a cheesy display if you want to see what is playing (at least in most vehicles).
Also - I said it earlier - but I still can't believe Metra used orange LED's for the buttons. They look white in their video, which wouldn't be quite as bad, but they had the car for development - how hard would it be to match the blue LED's. (And it's not like different trim level Focus's have different color illumination (like say a Civic SI vs. a base Civic, for example!!!)